Gene name:
Snrnp70 (Snrp70) ;
Protein name:
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa;U1-70K;snRNP70) ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Found in a pre-mRNA splicing complex with SFRS4, SFRS5, SNRNP70, SNRPA1, SRRM1 and SRRM2. Found in a pre-mRNA exonic splicing enhancer (ESE) complex with SNRNP70, SNRPA1, SRRM1 and TRA2B/SFRS10. Interacts with dephosphorylated SFRS13A and SFPQ. Interacts with NUDT21/CPSF5, CPSF6, SCAF11 and ZRANB2.
Function:
Mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA. The truncated isoform cannot bind U1-snRNA.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MTQFLPPNLL | ALFAPRDPIP | YLPPLEKLPH | EKHHNQPYCG | IAPYIREFED |
100:
PRDAPPPTRA | ETREERMERK | RREKIERRQQ | EVETELKMWD | PHNDPNAQGD |
150:
AFKTLFVARV | NYDTTESKLR | REFEVYGPIK | RIHMVYSKRS | GKPRGYAFIE |
200:
YEHERDMHSA | YKHADGKKID | GRRVLVDVER | GRTVKGWRPR | RLGGGLGGTR |
250:
RGGADVNIRH | SGRDDTSRYD | ERPGPSPLPH | RDRDRDRERE | RRERSRERDK |
300:
ERERRRSRSR | DRRRRSRSRD | KDERRRSRER | SKDKDRDRKR | RSSRSRERAR |
350:
RERERKEELR | GGGGGGGGGS | GGGGGGDMAE | PSEAGDGAPD | DGPPGELGPE |
400:
GPDGPEEKGR | DRDRERRRSH | RSERERRRDR | DRDRDREHKR | GERGSERGRD |
448:
EARGGGGSGQ | DNGLEGLGSD | GRDMYMEAEG | GDGYMAPENG | YLMEAAPE
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Bovine
ELISA Kit for Mouse U1 snRNP 70 kDa
ELISA Kit for Mouse U1 snRNP 70 kDa
ELISA Kit for Mouse U1 snRNP 70 kDa
CLIA Kit for Mouse U1 snRNP 70 kDa
CLIA Kit for Mouse U1 snRNP 70 kDa
CLIA Kit for Mouse U1 snRNP 70 kDa
Polyclonal Antibody for Mouse U1 snRNP 70 kDa
Polyclonal Antibody for Mouse U1 snRNP 70 kDa
Polyclonal Antibody for Mouse U1 snRNP 70 kDa
Monoclonal Antibody for Mouse U1 snRNP 70 kDa
Monoclonal Antibody for Mouse U1 snRNP 70 kDa
Monoclonal Antibody for Mouse U1 snRNP 70 kDa
Protein for Mouse U1 snRNP 70 kDa
Protein for Mouse U1 snRNP 70 kDa
Protein for Mouse U1 snRNP 70 kDa
R&D Technical Data
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Precision
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Recovery
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Linearity
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
strain :
C57BL/6J .
tissue :
Kidney .
tissue :
Testis .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 71-448 (ISOFORMS 1 AND 2)
strain :
BALB/c .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-408;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Embryonic brain .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH SCNM1;SUBCELLULAR LOCATION
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-408 AND SER-419;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .